Quantitative Network Biology

Kandersteg, Monday 19 November 2018 – Tuesday 20 November 2018

Monday November 19, 2018

12:00-12:30 Arrival and welcome coffee
12:30-12:40 Welcome: Vassily Hatzimanikatis (EPF Lausanne) and Carolin von Schoultz (LS2)
12:40-16:15 Session I: Physical models and emergent properties in biological systems
12:40-13:15

Beat Fierz (EPF Lausanne): "Probing dynamic chromatin organization on the single-molecule scale"

13:15-13:50

Attila Becskei (University of Basel): “The control of stochastic gene choice during neuronal differentiation”

13:50-14:00 Poster presentation 1: Jan Burri (ETH Zurich)
 

 “How pollen tubes perceive and overcome obstacles"

14:00-14:30 Coffee Break
14:30-14:40 Poster presentation 2: Aarti Krishnan (University of Geneva)
 

“Metabolic modeling of Toxoplasma gondii: toward stage-specific networks”

14:40-15:15

Niko Beerenwinkel (ETH Zurich): “Learning tumor phylogenies from single-cell data”

15:15-15:50

Michel Milinkovitch (University of Geneva): "Patterning of the vertebrate skin through mechanical and Turing instabilities"

15:50-16:15

Poster flashlight presentations

16:15-16:45

Coffee break

16:45-17:45

Keynote lecture: Johan Elf, University of Uppsala (Sweden)

17:45-19:00 Break
19:00-21:30

Dinner

21:00-23:00 Poster session and drinks


Tuesday November 20, 2018

09:00-12:10 Session II: AI/Machine learning in biology
09:00-09:35

Manfred Claassen (ETH Zurich): “(Un-)supervised learning of cell population structure from single-cell snapshot data”

09:35-10:10

Enkelejda Miho (FHNW Muttenz): “Artificial intelligence uncovers signatures of antibodies”

10:10-10:20 Poster presentation 3: Marc-Antoine Jacques (University of Bern)
 

"Machine learning-based mining of ERK and AKT biosensor time-series reveals new signatures of oncogenic signaling"

10:20-10:50

Coffee break

10:50-11:00 Poster presentation 4: Bruno Correia (EPF Lausanne)
 

“Molecular deep learning on protein surfaces for functional prediction and de novo design”

11:00-11:35

María Rodríguez-Martínez (IBM Research, Zurich): "Characterizing tumor heterogeneity with single cell proteomics"

11:35-12:10

Michael Stadler (FMI Basel): “Mammalian chromatin remodelers selectively mediate transcription factor binding”

12:10-13:15

Lunch Break


13:15-16:45 Session III: Systems biomedicine
13:15-13:50

Paola Picotti (ETH Zurich): “Probing protein structural changes on a proteome-wide scale”

13:50-14:25

Patrick Matthias (FMI Basel): “Towards a mechanistic and quantitative framework for virus uncoating”

14:25-14:35 Poster presentation 5: Vito Zanotelli (University of Zurich)
 

“Investigating microenvironment-to-cell signaling in 3D spheroids through imaging mass cytometry”

14:35-15:05

Coffee break

15:05-15:15 Poster presentation 6: Andreas Moor (University of Zurich and Weizmann Institute of Science)
 

"Spatial reconstruction of single enterocytes uncovers broad zonation along the intestinal villus axis"

15:15-15:50

Uwe Sauer (ETH Zurich): "Metabolic coordination through metabolite-protein interactions"

15:50-16:25

Bart Deplancke (EPF Lausanne): "The genetic and molecular determinants of circadian variation in Drosophila melanogaster"

16:25-16:45 Closing remarks: Vassily Hatzimanikatis (EPF Lausanne) and Attila Becskei (University of Basel)