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Olivier Buetzberger - "Leveraging Agilent's expertise in imaging and metabolic phenotyping in your cardiovascular research"

Cardiovascular research increasingly relies on advanced technologies to elucidate the complex metabolic and cellular mechanisms underlying heart diseases. The Agilent Seahorse XF Analyzer and the BioTek Cytation represent complementary tools that significantly enhance our ability to investigate cardiac function and pathology. The Agilent Seahorse XF Analyzer is instrumental in assessing mitochondrial function and cellular metabolism through real-time measurement of oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). This technology allows researchers to explore metabolic shifts in cardiomyocytes under various conditions and to evaluate the effects of therapeutic interventions on cardiac metabolism.

In conjunction with the Seahorse XF Analyzer, the BioTek Cytation provides comprehensive cellular imaging and quantitative analysis capabilities. Equipped with high-content screening and fluorescence microscopy, the Cytation system enables detailed examination of cardiomyocyte morphology, viability, and cellular signaling pathways. This is particularly useful for assessing the impact of genetic modifications, pharmacological treatments, and disease models on cardiac cells. The Cytation’s automated imaging and data analysis streamline high-throughput studies, facilitating large-scale investigations into cardiovascular health.